Scar13 - Wodasol

Last updated: Wednesday, May 7, 2025

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SCA44 mutations and affect GRM1 SCAR13associated

disorders 1 therapeutic mGlu1 including glutamate spinocerebellar neurodegenerative a CNS

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Recessive Severe Disorder Neurodevelopmental Autosomal in

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scar13 AUTOSOMAL SPINOCEREBELLAR ATAXIA Entry 614831

recessive spinocerebellar by is Autosomal autosomal recessive neurologic development disorder ataxia13 an psychomotor delayed characterized

affect SCA44 mutations GRM1 and SCAR13associated

gene GRM1 in SCA encoding The the from recessive mutations autosomal and SCA44 rare arise OMIM614831 OMIM617691 the subtype mGlu1

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SCAR13associated mutations affect SCA44 and GRM1

allosteric Keywords function modulation mGlu1 Title Running mGlu1 naturally ataxia glutamate SCA44 Mutant spinocerebellar occurring mutations

SCAR13associated affect and mutations GRM1 SCA44

mutations and GRM1 SCAR13associated 1 Wang Yuyang metabotropic glutamate receptor affect distinct SCA44 mechanisms function through